Mind Your Behind

The PAC Study in the News: Mass Media, Presentations, and Publications

Publications

Nyitray AG, Schick V, Swartz MD, Giuliano AR, Fernandez ME, Deshmukh AA, Ridolfi TJ, Ajala C, Brzezinski B, Sandoval M, Nedjai B, Smith JS, Chiao EY. Rationale and design of the Prevent Anal Cancer Self-Swab Study: A protocol for a randomised clinical trial of home-based self-collection of cells for anal cancer screening. BMJ Open. 2021 Jun 29;11(6):e051118. PMCID: PMC8245463.

Nitkowski J, Giuliano A, Ridolfi T, Chiao E, Fernandez ME, Schick V, Swartz MD, Smith JS, Schneider EA, Brzezinski B, Nyitray AG. Effect of the environment on home-based self-sampling kits for anal cancer screening. Journal of Virological Methods. 2022 Dec; 310:114616.; PMCID: PMC9645463.

Nyitray AG, Ridolfi TJ, Nitkowski J, McAuliffe TL, Deshmukh AA, Giuliano AR, Chiao EY; The Prevent Anal Cancer Self-Swab Study Team. Digital anal rectal examination usage among individuals at increased risk for anal cancer. Journal of Lower Genital Tract Disease. 2023 Jul 1;27(3):242-247. PMCID: PMC10313742.

Nyitray AG, Nitkowski J, McAuliffe TL, Brzezinski B, Swartz MD, Fernandez ME, Deshmukh AA, Ridolfi TJ, Lundeen SJ, Cockerham L, Wenten D, Petroll A, Hilgeman B, Smith JS, Chiao EY, Giuliano AR, Schick V, and the Prevent Anal Cancer Self-Swab Study Team. Home-based self-sampling vs clinician sampling for anal precancer screening: The Prevent Anal Cancer (PAC) Self-Swab Study. International Journal of Cancer. 2023 Aug 15;153(4):843-853. PMCID: PMC10330574.

Flores RA, Wilkerson JM, Travis A, Almirol E, Washington D, Weaver L, Liebert C, Chiao E, Hazra A, Nyitray AG. Men who have sex with men experience low anxiety and few barriers to performing anal self or companion examinations: A qualitative study of the Prevent Anal Cancer Palpation Study. Culture, Health and Sexuality. 2024;26(7):920-35. doi: 10.1080/13691058.2023.2263500. PMCID: PMC11001786.

Nitkowski J, Giuliano AR, Ridolfi T, Chiao E, Fernandez ME, Schick V, Swartz MD, Smith JS, Nyitray AG. Concordance of human papillomavirus genotypes in mailed home-based self-collected versus clinician-collected anal swabs among sexual and gender minority individuals. Sexually Transmitted Diseases. 2024;51(4):270-5. PMCID: PMC10978280.

Nyitray AG, McAuliffe TL, Liebert C, Swartz MD, Deshmukh AA, Chiao EY, Weaver L, Almirol E, Kerman J, Schneider JA, Wilkerson JM, Hwang LY, Smith D, Hazra A, and the Prevent Anal Cancer Palpation Study Team. The accuracy of anal self- and companion exams among sexual minority men and transgender women: A prospective analysis. The Lancet Regional Health - Americas. 2024; 31:100704. PMCID: PMC10910307

Nitkowski J, Ridolfi T, Lundeen SJ, Giuliano A, Chiao E, Fernandez M, Schick V, Smith J, Brzezinski B, Nyitray A. The influence of home versus clinic anal human papillomavirus sampling on high-resolution anoscopy uptake in the Prevent Anal Cancer Self-Swab Study. Sexual Health. 2024;21(3). doi: https://doi.org/10.1071/SH23210. PMID: 38683939; PMCID: pending.

Nitkowski J, Fernandez ME, Ridolfi T, Chiao E, Giuliano AR, Schick V, Swartz MD, Smith JS, Nyitray AG. The impact of body mass index and physical disability on home-based anal self-sampling. Cancer Causes and Control. 2024 Jan;35(1):161-166. doi: 10.1007/s10552-023-01775-y. PMID: 37632577; PMCID: pending.

Nitkowski J, Giuliano AR, Ridolfi T, Chiao E, Fernandez ME, Schick V, Swartz MD, Smith JS, Nyitray AG. Acceptability of anal human papillomavirus home self-sampling and clinician sampling among sexual and gender minority individuals in Milwaukee, Wisconsin: The Prevent Anal Cancer Self-Swab Study. LGBT Health. 2024 Jan;11(1):47-56. doi: 10.1089/lgbt.2023.0012. PMID: 37870947; PMCID: pending.

Nyitray AG, Rosser BRS, Hazra A, Nitkowski J, Smith D, Brzezinski B, Ridolfi TJ, Schneider JA, Chiao EY, Sanos S, Mkonyi E, Mgopa LR, Ross MW. Factors associated with decreased anal sphincter tone and the accuracy of forced anal examinations to detect individuals having receptive anal intercourse: An observational study. Accepted by BMJ Public Health on 2024 May 29.

Presentations

Nyitray AG. Novel Opportunities for Anal Cancer Screening Among Men, Cancer Center Annual Scientific Retreat, Medical College of Wisconsin, Milwaukee, WI, 4/26/2019

Nyitray AG. Novel Opportunities for Anal Cancer Screening Among Men, Annual Milwaukee HIV/STI Update Meeting, Center for AIDS Intervention Research, Medical College of Wisconsin, Milwaukee, WI, 8/13/2019

Nyitray AG, Ajala C, Brzezinski B, Deshmukh A, Hazra A, Schneider JA, Hwang LY, Swartz MD, Sydnor C, White M, Wilkerson JM, McAuliffe TL, Chiao EY. Protocol for the Prevent Anal Cancer (PAC) Palpation Study. 33rd International Papillomavirus Conference and Clinical Workshop, Barcelona, Spain, 7/20/2020

Nyitray AG, Ajala C, Brzezinski B, Swartz MD, Fernández ME, Ridolfi TJ, Lundeen SL, McAuliffe TL, Schick V, Smith JS, Giuliano AR, Nedjai B, Chiao EY. Protocol for the Prevent Anal Cancer (PAC) Self-Swab Study. 33rd International Papillomavirus Conference and Clinical Workshop, Barcelona, Spain, 7/20/2020

Nyitray AG. The Prevent Anal Cancer Study: Novel opportunities for anal cancer screening (with adjustment for COVID-19), American Association for Cancer Research 13th Conference on The Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, Miami, FL, 10/2/2020

Nyitray AG. The Prevent Anal Cancer Study: The assessment of novel opportunities for anal cancer screening during COVID-19, University of Arizona, Tucson, AZ, 10/14/2020

Nyitray AG. Prevent Anal Cancer Self-Swab Study: Study Overview, HIV Case Meeting, Sixteenth Street Community Health Center, Milwaukee, WI, 06/15/2021

Nyitray AG, Hazra A, Richardson A, Schneider JA, Chiao EY, Rosser BRS, Sanos S, Ross MW. Digital Anal Rectal Examinations (DARE) are not a sensitive test to detect persons with a history of receptive anal sex. 25th Congress of the World Association for Sexual Health, Cape Town, South Africa (Virtual), 9/9-12/2021

Nyitray AG. Anal cancer and novel screening strategies. 3rd Annual Cancer Disparities Virtual Symposium: Challenges in Cancer Care for Sexual and Gender Minorities, Milwaukee, WI, 09/18/2021

Kerman J, Flores R, Washington D, Almirol E, Hazra A, Nyitray AG. Sexual behavior as impacted by COVID-19 vaccine availability, National Sexual Health Conference, Virtual, 10/6-8/2021

Nyitray AG, Chiao EY, Deshmukh A, Schick V, Ridolfi T, Schneider JA, Swartz MD, Hwang L-Y, Fernandez ME, Wilkerson JM, Hazra A Tails of two cities: Anal canal lesion characteristics among sexual and gender minorities in Chicago and Milwaukee detected by Digital Anal Rectal Examination (DARE) (NCT04090060;NCT03489707). 34th International Papillomavirus Conference and Clinical Workshop, Toronto, Canada (Virtual), 11/15-19/2021

Almirol E, Hazra A, Flores R, Kerman J, Washington D, Nyitray AG. Sex in the Time of COVID-19 Vaccines, United States Conference on HIV/AIDS, Virtual, 12/2-3/2021

Nyitray AG. Care For Your Derrière: Prevent Anal Cancer (PAC) Study Results to Date, Virtual Community Presentation, Milwaukee, WI, 02/22/2022

Nyitray AG. HPV and anal cancer screening: Suitability of clinician-performed Digital Anal Rectal Exams for detection of HPV-associated palpable lesions, Session Co-Chair, EUROGIN, Düsseldorf, Germany, 04/10/2022

Scibior-Bentkowska D, Nedjai B, Saull M, Nyitray AG. Host plus viral genome methylation as a biomarker for precancers and cancer. EUROGIN, Düsseldorf, Germany, 04/10/2022

Nitkowski J, Giuliano A, Ridolfi T, Fernandez M, Schick V, Swartz J, Brzezinski B, Nyitray AG. Effects of environmental conditions on home-based self-sampling kits for anal cancer screening. EUROGIN, Düsseldorf, Germany, 04/11/2022

Nitkowski J, Giuliano A, Ridolfi T, Chiao E, Fernandez M, Schick V, Swartz MD, Smith JS, Brzezinski B, Nyitray AG. Effects of the environment on home-based self-sampling kits for anal cancer screening. Medical College of Wisconsin Cancer Center Annual Scientific Retreat. Discovery World Science and Technology Museum. Milwaukee, WI, 5/13/2022

Nyitray AG. Prevent Anal Cancer Self-Swab Study: Study Results Update, Sixteenth Street Community Health Center, Milwaukee, WI, 05/16/2022

Nitkowski J, Giuliano A, Ridolfi T, Chiao E, Fernandez M, Schick V, Swartz MD, Smith JS, Nyitray AG, and The Prevent Anal Cancer Study Team. Agreement of HPV genotypes in self- versus clinician-collected anal swabs among men who have sex with men (MSM) In Milwaukee, Wisconsin, USA: The Prevent Anal Cancer Self-Swab Study. 32nd Annual Medical College of Wisconsin Graduate School Research Poster Session. Milwaukee, WI. Poster. 10/27/2022

Nitkowski J, Giuliano A, Ridolfi T, Chiao E, Fernandez M, Schick V, Swartz MD, Smith JS, Nyitray AG, and The Prevent Anal Cancer Study Team. Comparing acceptability of home- versus clinic-based anal swabbing among men who have sex with men: The Prevent Anal Cancer Study. 2022 Annual Medical College of Wisconsin Community Engagement Poster Session. Milwaukee, WI. Poster. 11/3/2022

Nitkowski J, Giuliano AR, Ridolfi T, Chiao E, Fernandez M, Schick V, Swartz MD, Smith JS, Nyitray AG, and The Prevent Anal Cancer Study Team. Agreement of HPV genotypes in self- versus clinician-collected anal swabs among men who have sex with men (MSM) in Milwaukee, Wisconsin, USA: The Prevent Anal Cancer Self-Swab Study. European Research Organisation on Genital Infection and Neoplasia (EUROGIN) International Multidisciplinary HPV Congress. Bilbao, Spain. Oral presentation. February 2023

Nitkowski J, Giuliano AR, Ridolfi T, Chiao E, Fernandez M, Schick V, Swartz MD, Smith JS, Nyitray AG, and The Prevent Anal Cancer Study Team. Acceptability of anal HPV home self-sampling versus clinician sampling among men who have sex with men: The Prevent Anal Cancer Study. International Papillomavirus Society Conference (IPVC). Washington, D.C. Oral presentation. April 2023

Ross MW, Rosser BRS, Nyitray AG. Towards a More Holistic Approach to Gay Men’s Healthcare: Applying Lessons from Studies of Cancer among Gay and Bisexual Men to HIV/AIDS, AIDSImpact, Stockholm, Sweden, 6/13/2023

Nyitray AG. Home-based Anal Precancer Self-Screening Vs. Clinic Screening: Increased Engagement in Home-Based Screening with High Specimen Adequacy, the Prevent Anal Cancer Self-Swab Study. New York University Langone Health’s The Science of Cancer Health Equity in Sexual and Gender Minority Communities; Provocative Questions Symposium 3: SGM Cancer Screenings and Sexual Health. New York, NY, 10/7/2023.

Nitkowski J, Giuliano AR, Ridolfi T, Chiao E, Fernandez ME, Schick V, Swartz MD, Smith JS, and Nyitray AG. High-resolution Anoscopy Attendance and Acceptability in the Prevent Anal Cancer Self Swab Study (NCT03489707). 2023 Annual Medical College of Wisconsin Community Engagement Poster Session. Milwaukee, WI, 11/9/2023

Nitkowski, J, Nyitray, AG. The influence of home versus clinic anal human papillomavirus sampling on high-resolution anoscopy attendance in the Prevent Anal Cancer Self-Swab Study. EUROGIN, Stockholm, Sweden, 3/13/2024

Nyitray AG, Burchell A. Putting anal cancer screening into practice: Implementation science, biomarker development, and self-sampling. Session Co-Chair, EUROGIN, Stockholm, Sweden, 3/13/2024

Nyitray AG, Nitkowski J, Ridolfi T, Lundeen S, Chiao EY, Felix J. How might siloed biomarker development impact engagement with anal cancer screening? EUROGIN, Stockholm, Sweden, 3/13/2024

Scibior-Bentkowska D, Nyitray, AG. Host and viral genome methylation in detection of anal high-grade squamous intraepithelial lesions. EUROGIN, Stockholm, Sweden, 3/13/2024

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Reaching Out to LGBTQ+ Communities

PAC Study Principal Investigator Dr. Alan Nyitray featured for his work with the LGBTQ+ communities with colleague Dr. Malika Siker.
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MCW Cancer Center 2023 Scientific Retreat

PAC Study Principal Investigator, Alan Nyitray PhD (right), and PAC Study Coordinator Bridgett Brzezinski, MA (left), stand with PAC Study results-based scientific poster titled, “Home-based anal precancer screening vs clinic screening: Increased engagement in home-based screening with comparable adequacy, the Prevent Anal Cancer (PAC) Self-Swab Study.” The posted won “Best Poster” for Cancer Prevention and Outcomes at the Medical College of Wisconsin Cancer Center 2023 Scientific Retreat.
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MCW Cancer Center 2019 Scientific Retreat

PAC Study Coordinator Christopher Ajala, MD, MPH, presents a scientific poster on the PAC Study methodology titled, "Protocol of the Prevent Anal Cancer Study of Self-Swabbing and Novel Biomarkers," at the MCW Cancer Center 2019 Scientific Retreat.